FQ Group

Chemical Biology and Cell Biology

Chemical Biology and Cell Biology

About Group

The chromosome is mainly composed of nucleosomes formed by DNA entangled with histones, which are combined with a series of modification-interacting proteins, transcription factors, chromatin remodeling factors to form highly concentrated aggregates. Transposons, also known as 'jumping genes', can self-replicate and transfer to other random gene loci. They not only provide abundant genetic materials for biological evolution, but also play a key role in the adaptive evolution of species. They are one of the driving forces of genome evolution and an important source of biodiversity and complexity.

We are committed to spatio-temporal analysis of chromatin spatial proteome, and comprehensively apply interdisciplinary technology to the frontier research of decoding the mystery of life. We hope to provide a molecular theoretical basis for the screening and evolution of DNA fragments in the process of gene transposition, and the regulation of gene expression in time and space.

The chromosome is mainly composed of nucleosomes formed by DNA entangled with histones, which are combined with a series of modification-interacting proteins, transcription factors, chromatin remodeling factors to form highly concentrated aggregates. Transposons, also known as 'jumping genes', can self-replicate and transfer to other random gene loci. They not only provide abundant genetic materials for biological evolution, but also play a key role in the adaptive evolution of species. They are one of the driving forces of genome evolution and an important source of biodiversity and complexity.

We are committed to spatio-temporal analysis of chromatin spatial proteome, and comprehensively apply interdisciplinary technology to the frontier research of decoding the mystery of life. We hope to provide a molecular theoretical basis for the screening and evolution of DNA fragments in the process of gene transposition, and the regulation of gene expression in time and space.

Publication

Members

Xin Wen

Join the research group in 2025

Graduate student, Tianjin University

Get In Touch

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